How can dioxin affect so many parts of the body?

Dioxin binds very strongly to intracellular receptors in the nuclei of animal and human cells throughout the body. So dioxin can easily get into the nucleus, where the cell's DNA is located, and wreak havoc. If it damages the DNA, that could cause cancer or birth defects. It could also alter the DNA's instructions to make normal enzymes, hormones, and other proteins, which could lead to any of a number of diseases.