With the exception of skin cancer, the people at greatest risk for head and neck cancer are those with a history of years of using various forms of tobacco (i.e. cigarettes, cigars, snuff, chewing tobacco) and consumption of alcoholic beverages. These chronic irritants are responsible for mouth, throat, voice box and larynx cancer. Cancer of the sinuses occur because of long term exposure to carcinogens such as inhaled wood, dust, nickel, and various forms of carcinogenic chemicals. Skin cancers generally occur in people who have had prolonged sun exposure.